Holistic Medicine For Gut & Brain + Body & Mind

Programs To Transform Your Health So You Can Live With The Freedom Of Wellness & Resilience

Partnering With Patients

Hi, I’m Dr. Sara DeFrancesco. I help people turn their brains and health back on by healing root cause metabolic problems (like overlooked inflammatory triggers, stealth infections, and nutritional deficiencies) combined with holistic neuroscience so you can heal the cause of what is preventing you from being well.

Using the synergy of holistic medicine, functional medicine testing, neuroscience, and mind-body medicine I partner with patients to heal the gut-brain connection (and everything in between). This approach focuses on investigating and identifying the root cause of your health problems so we can remove obstacles to healing and correct imbalances, allowing dysfunctional systems to heal.

I work with patients seeking help for digestive problems, fatigue, insomnia, anxiety, depression, brain fog, memory problems, and autoimmune-neurological conditions. The first thing we do is set the diagnosis aside and focus on you and your story so we can unravel the triggers and events that derailed your health. Then we create a personalized plan to heal your root causes, release toxicity, and nourish your body so you can recreate wellness and build your resiliency.

When 7 minutes is the average doctor’s visit and it takes 17.5 years for today’s life changing research to be implemented in the average doctor’s office…

35 Million

Suffer from Irritable Bowel Syndrome (IBS).

40 Million

Anxiety is the most common “psychiatric disorder.”

Ages 15 - 43

Depression is the most common cause of disability for people ages 15 – 43.

1 in 5

People develop some form of neurodegeneration.

Without Ever Knowing Why

A Smarter Approach To Health

A personalized and proactive plan to heal the overlooked causes of your health concerns.

Data & testing to identify and resolve your inflammatory triggers (like chronic infections, toxic burden, and nutritional deficiencies to name a few).

Smart supplements and specific protocols customized for each phase of healing based on your root causes, lab testing, and history.

Mindset, Nutrition, & Lifestyle recommendations so you know exactly how to continously improve your health.

Education & support so you can successfully transform health outcomes for you and your family.


Dr. DeFrancesco is amazing! She is thorough to find the root causes to ailments, with the right testing, the right gut health approach, and education. I appreciate the time, thoughtfulness, and work that goes into each of my appointments with her. I will forever be grateful for working with Dr. DeFrancesco after seeing several other MDs, NDs, chiropractors, and massage therapists. I am finding answers to struggles I have been having for ten plus years!

– Jennifer F.

When modern medicine failed me, Dr. Sara came to the rescue! Her tests, diagnosis, and treatment were 100% accurate. I was completely healed and fully restored in 6 months.

– Amy S.

Could not be happier. Possibly the best decision I've ever made.

Kirby C.

I have had such a positive experience working with Dr. Sara. She recommended a series of lab tests that helped me find my root cause, and then started me on a regime of supplements to start the cleansing and healing. We also changed my thyroid medicine, and I have seen huge improvements with energy and clarity. Thank you Dr. Sara DeFrancesco!

– Michelle E.

Start Your Personalized Root Cause Program Today

Comprehensive programs to eliminate symptom overwhelm, uncover overlooked causes of your health problems, and provide you with a step-by-step process to transform your health.

Weight Loss

Health Transformation

Popular Articles

Why Weight Loss Programs Fail & How To Reset Your Metabolism

Why Do Most Weight Loss Programs Fail? Holistic, healthy, sustainable weight loss is the key to getting the results you want (and keeping them!). But many programs fail because they create more stress on your metabolism instead of working to heal it. Most conventional...

3 Essential Stress Relievers For Autoimmunity

If you're dealing with autoimmunity or a chronic inflammatory condition, you've probably noticed that your symptoms tend to wax and wane and sometimes it's difficult to figure out what makes you feel better or worse. You might have tried to pin down the cause of your...

The 3 Step Strategy To Heal Digestive,

Mood, & Memory Problems

Fix Your Gut Brain Connection